1. Home
  2. Southern Africa
  3. Angola

New treatment for sleeping sickness

[DRC] Diganosing sleeping sickness is a hightech operation. [Date picture taken: 05/23/2006] Hugo Rämi/IRIN
Diagnosing sleeping sickness is a hightech operation - file photo
Patients at an advanced stage of Human African Trypanosomiasis, or sleeping sickness, can now access more convenient, safer and cheaper treatment after the introduction of Nifurtimox-Eflornithine Combination Therapy (NECT).

Developed by the Drugs for Neglected Diseases Initiative (DNDi) and partners, NECT comprises the administration of oral nifurtimox, and eflornithine injections for 10 days.

Past treatment has either been the widely-used arsenic-based melarsoprol injections, which kill an estimated five percent of patients, or eflornithine monotherapy, which requires 56 one-hour infusions in 14 days.

The diagnosis of sleeping sickness, which is spread by the bite of an infected tsetse fly, involves puncturing the lower back (lumbar) for a spinal fluid sample to determine whether parasites have invaded the brain.

Brain invasion in advanced stages leads to problems such as confusion, personality changes, slurred speech, seizures, and difficulty walking and talking - left untreated, the disease is fatal. At the initial stages, symptoms include fever and aching muscles and joints.

Sleeping sickness is endemic in 36 African countries and affects an estimated 50,000 to 70,000 people at any one time.

DNDi estimates that NECT will cost about 223 Euros (about 232 $US), half the cost of eflornithine monotherapy.

aw/am

This article was produced by IRIN News while it was part of the United Nations Office for the Coordination of Humanitarian Affairs. Please send queries on copyright or liability to the UN. For more information: https://shop.un.org/rights-permissions

Share this article

Get the day’s top headlines in your inbox every morning

Starting at just $5 a month, you can become a member of The New Humanitarian and receive our premium newsletter, DAWNS Digest.

DAWNS Digest has been the trusted essential morning read for global aid and foreign policy professionals for more than 10 years.

Government, media, global governance organisations, NGOs, academics, and more subscribe to DAWNS to receive the day’s top global headlines of news and analysis in their inboxes every weekday morning.

It’s the perfect way to start your day.

Become a member of The New Humanitarian today and you’ll automatically be subscribed to DAWNS Digest – free of charge.

Become a member of The New Humanitarian

Support our journalism and become more involved in our community. Help us deliver informative, accessible, independent journalism that you can trust and provides accountability to the millions of people affected by crises worldwide.

Join